产品货号：
Z27813
中文名称：
Syntaphilin/SNPH抗体
英文名称：
Anti-Syntaphilin/SNPH Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Syntaphilin/SNPH Antibody |
| 指标别名 | KIAA0374;SNPH;syntaphilin |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | SNPH |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Syntaphilin antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human Syntaphilin.The immunogen is located within amino acids 80 - 130 of Syntaphilin. |
| 计算分子量 | 54kDa |
| 成分 | Syntaphilin Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Syntaphilin Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Syntaphilin was initially identified in a yeast two-hybrid screen with the carboxy terminal region of Syntaxin-1 as bait.Syntaxin-1 is a key component of the synaptic vesicle docking machinery that forms the SNARE complex with synaptobrevin and SNAP-25.Syntaphilin competes with SNAP-25 for binding to syntaxin-1 and inhibits the formation of the SNARE complex,thereby potentially regulating synaptic vesicle exocytosis.Syntaphilin also binds dynamin-1 and inhibits dynamin-dependent endocytosis.Mice lacking syntaphilin show an increased level of mitochondrial motility and a reduced density of axonal mitochondria.This correlates with an enhanced short-term facilitation and significant impairments in motor ability,suggesting syntaphilin plays a major role in presynaptic function.Multiple isoforms are known to exist. |
| Uniprot ID | O15079 |
| 基因名全称 | Syntaphilin |
| 蛋白名全称 | Syntaphilin |
| 推荐稀释比 | Syntaphilin antibody can be used for detection of Syntaphilin by Western blot at 2 ～ 4μg/mL.Despite its predicted molecular weight,Syntaphilin usually migrates at higher molecular weight in SDS-PAGE.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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