产品货号：
Z27708
中文名称：
SPRED1抗体
英文名称：
Anti-SPRED1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SPRED1 Antibody |
| 指标别名 | NFLS;hSpred1;spred-1;Sprouty-related;EVH1 domain-containing protein 1;Spred-1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | SPRED1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Spred1 antibody was raised against a 20 amino acid synthetic peptide near the center of the human Spred1.The immunogen is located within amino acids 120 - 170 of Spred1. |
| 计算分子量 | 50kDa |
| 成分 | Spred1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Spred1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The Ras-MAP kinase pathway is essential for the differentiation of neuronal cells and myocytes;it is inhibited by Spred1,a member of the Sprouty family of proteins.Spred1 acts by suppressing the phosphorylation and activation of Raf.The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis.Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC),suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC.Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).This Spred1 antibody is predicted to have no cross-reactivity to Spred2 or Spred3. |
| Uniprot ID | Q7Z699 |
| 基因名全称 | Sprouty-related,EVH1 domain containing 1 |
| 蛋白名全称 | Sprouty-related,EVH1 domain containing 1 |
| 推荐稀释比 | Spred1 antibody can be used for detection of Spred1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.Antibody validated:Western Blot in mouse samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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