产品货号：
Z27625
中文名称：
STING/TMEM173抗体
英文名称：
Anti-STING/TMEM173 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-STING/TMEM173 Antibody |
| 指标别名 | hMITA;hSTING;Mediator of IRF3 activation;MITA;MPYS;NET23;STING;STING1;TMEM173;TMEM173/STING;transmembrane protein 173 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | TMEM173 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-MPYS antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human MPYS.The immunogen is located within amino acids 260-310 of MPYS. |
| 计算分子量 | 42kDa |
| 成分 | MPYS Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | MPYS Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | MPYS antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | MPYS is a recently identified plasma membrane tetraspanner that is associated with major histocompatibility complex class II (MHC-II) and mediates its transduction of apoptotic signals.It has also been found to be associated with VISA,a mitochondrial protein that acts as an adaptor in virus-triggered signaling.MPYS also interacts with IRF3 and recruits the kinase TBK1 to the VISA-associated complex,acting as a critical mediator of virus-triggered IRF3 activation and interferon (IFN) expression.It is thought that the binding of nucleic acid to the innate immune protein RIG-I causes complex formation between RIG-I,VISA,and MPYS.This complex then recruits TBK1 to phosphorylate IRF3 which then directly activates IFN transcription.At least three isoforms of MPYS are known to exist. |
| Uniprot ID | Q86WV6 |
| 基因名全称 | Transmembrane protein 173 |
| 蛋白名全称 | Transmembrane protein 173 |
| 推荐稀释比 | WB:1～2μg/mL;ICC:5μg/mL;IF:20μg/mL.Antibody validated:Western Blot in human and mouse samples;Immunocytochemistry and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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