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产品目录

SR-BI/SCARB1抗体图片
产品货号:
Z27581
中文名称:
SR-BI/SCARB1抗体
英文名称:
Anti-SR-BI/SCARB1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-SR-BI/SCARB1 Antibody
指标别名CD36 and LIMPII analogous 1;CD36 antigen like 1;CD36L1;CLA 1;CLA1;SCARB1;SRB1;SR-B1;SR-BI
克隆性Polyclonal
检验物种mouse,rat
应用范围WB,IHC,ICC,FCM
基因名称SCARB1
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminus of mouse SCARB1 (478-509aa KKGSQDKEAIQAYSESLMSPAAKGTVLQEAKL),different from the related rat sequence by one amino acid.
实际分子量85KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Scavenger receptor class B member 1 (SRB1),also known as SR-BI,is a protein that in humans is encoded by the SCARB1 gene.SR-BI functions as a receptor for high-density lipoprotein.Scavenger receptor class B,type I (SR-BI) is an integral membrane protein found in numerous cell types/tissues,including the liver and adrenal.It is best known for its role in facilitating the uptake of cholesteryl esters from high-density lipoproteins in the liver.This process drives the movement of cholesterol from peripheral tissues towards the liver for excretion.This movement of cholesterol is known as reverse cholesterol transport and is a protective mechanism against the development of atherosclerosis,which is the principal cause of heart disease and stroke.SR-BI has also been identified in the livers of non-mammalian species (turtle,goldfish,shark,chicken,frog,and skate),suggesting it emerged early in vertebrate evolutionary history.The turtle also seems to upregulate SB-RI during egg development,indicating that cholesterol efflux may be at peak levels during developmental stages.
Uniprot IDQ61009
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称scavenger receptor class B,member 1
蛋白名全称Scavenger receptor class B member 1
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunocytochemistry 1:50~400
Flow cytometry (FCM) 1~3μg/1×106 cells
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 22 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:SR-BI/SCARB1抗体SR-BI抗体SCARB1多抗Anti-SR-BI/SCARB1 Antibody
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