产品货号：
Z27569
中文名称：
SPTLC2抗体
英文名称：
Anti-SPTLC2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SPTLC2 Antibody |
| 指标别名 | KIAA0526,LCB 2,LCB2,LCB2a,Serine palmitoyltransferase 2,SPT 2,SPT2,SPTLC2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | SPTLC2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-SPT2 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human SPT2.The immunogen is located within the last 50 amino acids of SPT2. |
| 计算分子量 | 63kDa |
| 成分 | SPT2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SPT2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Serine palmitoyltransferase (SPT),which consists of two different subunits,is the key enzyme in sphingolipid biosynthesis.It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor.SPT2 is the long chain base subunit 2 of mammalian serine palmitoyltransferase.SPT2 is catalytically active but needs its related protein SPT1 for its stabilization and anchoring the holoenzyme to the cytosolic face of the endoplasmic reticulum.As in the case with SPT1,mutations in the SPT2 gene can cause hereditary sensory and autonomic neuropathy type I (HSAN-I),resulting from a loss of SPT activity as well as the accumulation of the atypical and neurotoxic sphingoid metabolite 1-deoxy-sphinganine. |
| Uniprot ID | O15270 |
| 基因名全称 | Serine palmitoyltransferase,long chain base subunit 2 |
| 蛋白名全称 | Serine palmitoyltransferase,long chain base subunit 2 |
| 推荐稀释比 | WB:0.5～1μg/mL;ICC:10μg/mL;IF:20μg/mL.Antibody validated:Western Blot in human and mouse samples;Immunocytochemistry in mouse samples;Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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