产品货号:
Z27469
中文名称:
STEAP1抗体
英文名称:
Anti-STEAP1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-STEAP1 Antibody |
指标别名 | Metalloreductase STEAP1,PRSS24,STEAP,STEAP1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC |
基因名称 | STEAP1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | STEAP1 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human STEAP1.The immunogen is located within the last 50 amino acids of STEAP1. |
计算分子量 | 40kDa |
成分 | STEAP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | STEAP1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The six-transmembrane epithelial antigen of prostate 1 (STEAP1) was the first member of a family of metalloreductases identified as cell-surface antigens in prostate tissue.The normal function of STEAP is still uncertain;unlike other members of the STEAP family,STEAP1 does not promote iron or copper reduction or uptake and lacks the FNO-like reductase domain critical for activity.However,its expression is highly increased in multiple cancer cell lines,including prostate,bladder,colon,and ovarian cancers.Supporting this is evidence that STEAP1 peptides can be used to stimulate CD8+ T cells from healthy donors,enabling them to recognize STEAP1-positive human tumor cells,suggesting that STEAP1 may a potential target for cancer immunotherapy.At least three isoforms of STEAP1 are known to exist. |
Uniprot ID | Q9UHE8 |
基因名全称 | Six transmembrane epithelial antigen of the prostate 1 |
蛋白名全称 | Six transmembrane epithelial antigen of the prostate 1 |
推荐稀释比 | STEAP1 antibody can be used for detection of STEAP1 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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