产品货号：
Z27419
中文名称：
STAT5B抗体
英文名称：
Anti-STAT5B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-STAT5B Antibody |
| 指标别名 | STAT5;STAT5B |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | STAT5B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human STAT5b(767-787aa RRVEELLGRPMDSQWIPHAQS),identical to the related rat and mouse sequences. |
| 实际分子量 | 90～95KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | STAT5B(Signal transducer and activator of transcription 5B) is a protein that in humans is encoded by the STAT5B gene.STAT5B orthologs have been identified in most placentals for which complete genome data are available.By FISH,Lin et al.(1996) mapped STAT5B to 17q11.2.The protein encoded by this gene is a member of the STAT family of transcription factors.In response to cytokines and growth factors,STAT family members are phosphorylated by the receptor associated kinases,and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.This protein mediates the signal transduction triggered by various cell ligands,such as IL2,IL4,CSF1,and different growth hormones.It has been shown to be involved in diverse biological processes,such as TCR signaling,apoptosis,adult mammary gland development,and sexual dimorphism of liver gene expression.This gene was found to fuse to retinoic acid receptor-alpha(RARA) gene in a small subset of acute promyelocytic leukemias(APML).The dysregulation of the signaling pathways mediated by this protein may be the cause of the APML. |
| Uniprot ID | P51692 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | signal transducer and activator of transcription 5B |
| 蛋白名全称 | Signal transducer and activator of transcription 5B |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：STAT5B抗体，STAT5B多抗，Anti-STAT5B Antibody