产品货号：
Z27391
中文名称：
SPRY4抗体
英文名称：
Anti-SPRY4 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SPRY4 Antibody |
| 指标别名 | Protein sprouty homolog 4;sprouty homolog 4 (Drosophila);Spry 4;SPRY4 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,IHC,WB |
| 基因名称 | SPRY4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-Terminal region near amino acids 275-299 of Human Sprouty-4 protein. |
| 计算分子量 | 33kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity purified antibody is directed against human Sprouty-4 protein.The product was affinity purified from monospecific antiserum by immunoaffinity purification.A BLAST analysis was used to suggest reactivity with this protein from human and chimpanzee based on 100% homology for the immunogen sequence.Cross-reactivity is expected with Sprouty-4. |
| 浓度 | 1.1mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Sprouty-4 (also known as SPRY4) is an inhibitor of the insulin receptor and EGFR-transduced mitogen-activated protein kinase (MAPK) signaling pathway downstream of FGF and EGF receptor tyrosine kinase activation.It is positioned upstream of RAS activation and impairs the formation of active GTP-RAS.SPRY4 is widely expressed,with different isoforms.The protein consists of 322 amino acids,with a cysteine-rich region,Src homology 3 binding regions,proline-rich regions,and a PEST sequence.It is expressed predominantly in the cytoplasm.Northern results show bands across most tissues,with strongest expression in heart,brain,placenta,lung,and intestine. |
| Uniprot ID | Q9C004 |
| 基因名全称 | Protein sprouty homolog 4 |
| 推荐稀释比 | ELISA:1:3,000 - 1:12,000 IHC:1μg/mL to 10μg/mL WB:1:100 - 1:1,000 |
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