产品货号:
Z27370
中文名称:
SUPT6H抗体
英文名称:
Anti-SUPT6H Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-SUPT6H Antibody |
| 指标别名 | emb 5;hSPT6;KIAA0162;SPT6;SPT6H;SUPT6H;Tat cotransactivator 2 protein;Tat CT2 protein |
| 克隆性 | Polyclonal |
| 检验物种 | human,monkey,mouse,rat |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | SUPT6H |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Spt6/SUPT6H recombinant protein (Position:A564-Q1639). |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Transcription elongation factor SPT6 is a protein that in humans is encoded by the SUPT6H gene.SUPT6H (suppressor of Ty6 homolog),also known as SPT6,SPT6H,Tat-CT2 (Tat-cotransactivator 2 protein) or emb-5 in C.elegans,is a 1,726 amino acid protein that is highly conserved from yeast to humans.Expressed ubiquitously,SUPT6H localizes to the nucleus and contains one SH2 domain and one S1 domain.SUPT6H participates in both DRB (5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole)-mediated transcriptional inhibition as well as the enhancement of transcriptional elongation by the RNA polymerase II (Pol II).SUPT6H interacts with the nuclear proteins SPT4 and SPT5,which comprise the DSIF (DRB-sensitivity-inducing factor) complex that binds RNA polymerase II,and directly regulates elongation.Via its C-terminus,SUPT6H can also interact with Histone H3.Due to alternative splicing events,three isoforms exist for SUPT6H.This antibody specifically recognizes the 230kd phosphorylated SUPT6H protein. |
| Uniprot ID | Q7KZ85 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | SPT6 homolog,histone chaperone and transcription elongation factor |
| 蛋白名全称 | Transcription elongation factor SPT6 |
| 推荐稀释比 | Western blot(WB) 1:500~2000 Flow cytometry (FCM) 1~3μg/1×106 cells ELISA 1:100~1000 |
相关搜索:SUPT6H抗体,SUPT6H多抗,Anti-SUPT6H Antibody
