产品货号：
Z27224
中文名称：
STK39抗体
英文名称：
Anti-STK39 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-STK39 Antibody |
| 指标别名 | serine/threonine kinase 39;DCHT;PASK;SPAK;STK39 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC |
| 基因名称 | STK39 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PDCD5 antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human PDCD5.The immunogen is located within the first 50 amino acids of PDCD5. |
| 计算分子量 | 59kDa |
| 成分 | PDCD5 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PDCD5 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Programmed cell death 5 (PDCD5),a human apoptosis-related protein,is thought to play an early and universal role in apoptosis.PDCD5 is widely expressed and is upregulated in cells undergoing apoptosis,where it translocates rapidly from the cytoplasm to the nucleus.PDCD5 has a compact core structure of low flexibility with two mobile alpha-helices at N-terminal and a flexible unstructured C-terminal region.The charged residues are crucial for the ability of apoptosis-promoting and cell translocation of the protein.PDCD5 can facilitate apoptosis and enhance TAJ/TROY-induced paraptosis-like cell death.PDCD5 may play a dual role in the Tip60 pathway.It interacts with Tip60 and functions as a Tip60 co-activator to promote apoptosis.The nucleotide polymorphisms in the 5'-upstream region of?PDCD5 affect promoter activity and the susceptibility of a Chinese population to develop chronic myelogenous leukemia and may represent a novel tumor suppressor gene influencing lung cancer. |
| Uniprot ID | Q9UEW8 |
| 基因名全称 | Serine threonine kinase 39 (STE20/SPS1 homolog,yeast) |
| 蛋白名全称 | Serine threonine kinase 39 (STE20/SPS1 homolog,yeast) |
| 推荐稀释比 | PDCD5 antibody can be used for detection of PDCD5 by Western blot at 2.5μg/mL.Antibody can also be used for immunocytochemistry starting at 5μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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