产品货号：
Z27223
中文名称：
STK39抗体
英文名称：
Anti-STK39 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-STK39 Antibody |
| 指标别名 | serine/threonine kinase 39;DCHT;PASK;SPAK;STK39 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | STK39 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Stk39 antibody was raised against a 18 amino acid synthetic peptide from near the center of human Stk39.The immunogen is located within amino acids 360 - 410 of Stk39. |
| 计算分子量 | 59kDa |
| 成分 | Stk39 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Stk39 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The serine/threonine kinase Stk39 belongs to the STE20 family,a group of kinases that are known to interact with inflammation-related kinases (such as p38,JNK,NKCC1,PKC-theta,WNK and MLCK),and with transcription factor AP-1.The STE 20 family is involved in diverse biological phenomena,including cell differentiation,cell transformation/proliferation,cytoskeleton rearrangement,and the regulation of ion transporters.STK39 contains an N-terminal series of proline and alanine repeats (PAPA box),followed by a serine/threonine kinase catalytic domain and is abundantly expressed in the brain.STK39 is activated in response to hypotonic stress,leading to phosphorylation of several cation-chloride-coupled co-transporters.The catalytically active kinase specifically activates the p38 MAP kinase pathway,and its interaction with p38 decreases upon cellular stress,suggesting that this kinase may serve as an intermediate in the response to cellular stress.Recent studies show that?STK39 tend to be a novel candidate gene for autism and hypertension. |
| Uniprot ID | Q9UEW8 |
| 基因名全称 | Serine threonine kinase 39 (STE20/SPS1 homolog,yeast) |
| 蛋白名全称 | Serine threonine kinase 39 (STE20/SPS1 homolog,yeast) |
| 推荐稀释比 | Stk39 antibody can be used for detection of Stk39 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.Antibody validated:Western Blot in rat samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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