产品货号：
Z27220
中文名称：
SMMHC/MYH11抗体
英文名称：
Anti-SMMHC/MYH11 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SMMHC/MYH11 Antibody |
| 指标别名 | MYH11;Myosin 11;Myosin heavy chain 11;SMHC;SMMHC;SMM-HC;smooth muscle myosin heavy chain |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ChIP-seq,ChIP-qPCR,ChIP |
| 基因名称 | MYH11 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This antibody is raised in rabbit against human MYH11 (Myosin,Heavy Chain 11) using two KLH-conjugated synthetic peptides containing sequences from the C-terminal region of the protein. |
| 计算分子量 | 227kDa |
| 成分 | Whole antiserum from rabbit containing 0.05% azide. |
| 纯化方式 | Whole antiserum |
| 浓度 | 0.5～1mg/mL,actual concentration vary by lot.Use suggested dilution ratio to decide dilution procedure. |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | MYH11 is a smooth muscle myosin belonging to the myosin heavy chain family which function as major contractile proteins.MYH11 is involved in a pericentric inversion of chromosome 16 (inv (16) (p13q22)) which produces a chimeric transcript consisting of the N terminus of CBFb and the C-terminal portion MYH11.This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype.References citing this antibody (1) Mandoli A,Singh AA,Jansen PWTC,Wierenga ATJ,Riahi H,Franci G,Prange K,Saeed S,Vellenga E,Vermeulen M,Stunnenberg HG and Martens JHA (2013) CBFB–MYH11/RUNX1 together with a compendium of hematopoietic regulators,chromatin modifiers and basal transcription factors occupies self-renewal genes in inv (16) acute myeloid leukemia.Leukemia:1-9. |
| Uniprot ID | P35749 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot.Biorab recommends high sensitivity ChIP-seq Kit (CK1001 & CK1002) for Chromatin Immunoprecipitation. |
| 基因名全称 | Myosin-11 |
| 蛋白名全称 | Myosin-11 |
| 推荐稀释比 | User need to optimize the dilution ratio for this antibody |
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