
产品货号:
Z27209
中文名称:
SMMHC/MYH11抗体
英文名称:
Anti-SMMHC/MYH11 antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SMMHC/MYH11 antibody |
指标别名 | MYH11;Myosin 11;Myosin heavy chain 11;SMHC;SMMHC;SMM-HC;smooth muscle myosin heavy chain |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ICC/IF,ELISA |
基因名称 | MYH11 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human SMMHC/MYH11 recombinant protein (Position:E1206-S1315). |
实际分子量 | 228KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | MYH11 is a smooth muscle myosin belonging to the myosin heavy chain family which function as major contractile proteins.MYH11 is involved in a pericentric inversion of chromosome 16 (inv(16)(p13q22)) which produces a chimeric transcript consisting of the N terminus of CBFb and the C-terminal portion MYH11.This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype.References citing this antibody(1) Mandoli A,Singh AA,Jansen PWTC,Wierenga ATJ,Riahi H,Franci G,Prange K,Saeed S,Vellenga E,Vermeulen M,Stunnenberg HG and Martens JHA (2013) CBFB-YH11/RUNX1 together with a compendium of hematopoietic regulators,chromatin modifiers and basal transcription factors occupies self-renewal genes in inv(16) acute myeloid leukemia.Leukemia:1-9. |
Uniprot ID | P35749 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
基因名全称 | myosin heavy chain 11 |
蛋白名全称 | Myosin-11 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry (IHC) 1:50~400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Enzyme linked immunosorbent assay (ELISA) 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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