产品货号:
Z27081
中文名称:
SMAC/Diablo抗体
英文名称:
Anti-SMAC/Diablo Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SMAC/Diablo Antibody |
指标别名 | DIABLO;diablo homolog (Drosophila);Diablo homolog;mitochondrial;DIABLO S;SMAC;SMAC3 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
基因名称 | DIABLO |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human Smac/Diablo recombinant protein (Position:A56-D239).Human Smac/Diablo shares 88.6% amino acid (aa) sequence identity with mouse Smac/Diablo. |
实际分子量 | 25KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Diablo homolog (DIABLO),also referred to as second mitochondria-derived activator of caspases or SMAC,is a mitochondrial protein that in humans is encoded by the DIABLO (direct IAP binding protein with low pI) gene on chromosome 12.The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis,and allows activation of caspases by binding to inhibitor of apoptosis proteins.Overexpression of the encoded protein sensitizes tumor cells to apoptosis.A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64.Alternative splicing results in multiple transcript variants encoding different isoforms. |
Uniprot ID | Q9NR28 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | diablo,IAP-binding mitochondrial protein |
蛋白名全称 | Diablo homolog,mitochondrial |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry (IHC) 1:50~400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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