产品货号：
Z27066
中文名称：
SMAC/Diablo抗体
英文名称：
Anti-SMAC/Diablo Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SMAC/Diablo Antibody |
| 指标别名 | DIABLO;diablo homolog (Drosophila);Diablo homolog;mitochondrial;DIABLO S;SMAC;SMAC3 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | DIABLO |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This whole rabbit serum was prepared by repeated immunizations with recombinant His6-tagged human Smac/DIABLO protein (amino acids 56-239). |
| 计算分子量 | 27kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This antiserum is directed against human Smac/DIABLO and is useful in determining its presence in various assays. |
| 浓度 | 85mg/mL by Refractometry |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Apoptosis is a conserved cell suicide program essential for the development and homeostasis of multi-cellular organisms.Abnormal inhibition of apoptosis is a hallmark of cancer and autoimmune diseases,whereas excessive cell death is found in neurodegenerative disorders such as Alzheimers disease.Executioners of the apoptotic program are cysteine proteases termed caspases that exist as inactive zymogens in living cells and are activated during apoptosis.Active caspases cleave key intracellular protein substrates,resulting in the characteristic morphological changes associated with apoptosis.The release of cytochrome c from the mitochondria triggers the oligomerization of Apaf-1 in an ATP/dATP-dependent manner and induces the autoactivation of caspase-9.?Active caspase-9 in turn activates downstream effector caspases including caspase -3,-6 and -7. |
| Uniprot ID | Q9NR28 |
| 基因名全称 | Diablo homolog,mitochondrial |
| 推荐稀释比 | ELISA:1:5,000 - 1:20,000 IP:1:100 WB:1:1,000 - 1:2,000 |
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