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所在位置:所有产品 > 抗体抗原 > 一抗 > SNAI2抗体
SNAI2抗体图片
产品货号:
Z27004
中文名称:
SNAI2抗体
英文名称:
Anti-SNAI2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-SNAI2 Antibody
指标别名Protein snail homolog 2;SLUG;SLUGH;SLUGH1;SNAI2;snail homolog 2 (Drosophila);WS2D;Zinc finger protein SNAI2
克隆性Polyclonal
检验物种human,mouse
应用范围ELISA,WB
基因名称SNAI2
抗体来源Rabbit
抗体类型IgG
免疫原Slug antibody was raised against a 14 amino acid synthetic peptide from near the center of human Slug.The immunogen is located within amino acids 70 - 120 of Slug.
计算分子量30kDa
成分Slug Antibody is supplied in PBS containing 0.02% sodium azide.
纯化方式Slug Antibody is affinity chromatography purified via peptide column.
浓度1mg/mL
产品形态溶液
保存条件4℃可保存3个月,-20℃可保存1年。
背景资料Slug,a member of the Snail family of C2H2-type zinc finger transcription factors,was initially identified to be involved in epithelial-mesenchymal transitions as well as the formation of the neural tube during vertebrate embryogenesis.Like Snail,Slug transcription can be induced by growth factors such as FGF,BMP,and TGF-beta.Once expressed,Slug will bind E-box regions of promoters and repress transcription of genes such as E-cadherin and Claudin-1.More recently,its expression in breast,esophogeal,and colorectal carcinomas has been correlated with poor prognosis for survival.Furthermore,Slug can protect hemapoietic progenitor cells from radiation-induced apoptosis by repressing the p53-mediated transcription of Puma,a BH3-only antagonist of the anti-apoptotic members of the Bcl-2 family.Slug antibody has no cross-reactivity to Snail protein.
Uniprot IDO43623
基因名全称Snail homolog 2 (Drosophila)
蛋白名全称Snail homolog 2 (Drosophila)
推荐稀释比Slug antibody can be used for detection of Slug by Western blot at 1 to 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested.

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