产品货号:
Z27004
中文名称:
SNAI2抗体
英文名称:
Anti-SNAI2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-SNAI2 Antibody |
| 指标别名 | Protein snail homolog 2;SLUG;SLUGH;SLUGH1;SNAI2;snail homolog 2 (Drosophila);WS2D;Zinc finger protein SNAI2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | SNAI2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Slug antibody was raised against a 14 amino acid synthetic peptide from near the center of human Slug.The immunogen is located within amino acids 70 - 120 of Slug. |
| 计算分子量 | 30kDa |
| 成分 | Slug Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Slug Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | Slug,a member of the Snail family of C2H2-type zinc finger transcription factors,was initially identified to be involved in epithelial-mesenchymal transitions as well as the formation of the neural tube during vertebrate embryogenesis.Like Snail,Slug transcription can be induced by growth factors such as FGF,BMP,and TGF-beta.Once expressed,Slug will bind E-box regions of promoters and repress transcription of genes such as E-cadherin and Claudin-1.More recently,its expression in breast,esophogeal,and colorectal carcinomas has been correlated with poor prognosis for survival.Furthermore,Slug can protect hemapoietic progenitor cells from radiation-induced apoptosis by repressing the p53-mediated transcription of Puma,a BH3-only antagonist of the anti-apoptotic members of the Bcl-2 family.Slug antibody has no cross-reactivity to Snail protein. |
| Uniprot ID | O43623 |
| 基因名全称 | Snail homolog 2 (Drosophila) |
| 蛋白名全称 | Snail homolog 2 (Drosophila) |
| 推荐稀释比 | Slug antibody can be used for detection of Slug by Western blot at 1 to 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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