产品货号：
Z26996
中文名称：
SOCS1抗体
英文名称：
Anti-SOCS1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SOCS1 Antibody |
| 指标别名 | SOCS1;TIP3;SOCS-1;TIP-3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | SOCS1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human SOCS1(197-211aa NPVLRDYLSSFPFQI),identical to the related mouse and rat sequences. |
| 实际分子量 | 24KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Suppressor of cytokine signaling 1(SOCS1),also known as Jak-binding protein(JAB),is a negative regulator to a subset of protein-tyrosine kinases.This 211-amino acid protein has a molecular mass of about 23.5kD.The TEC-binding region of SOCS1 resides in the N terminus.SOCS1 associates with Tec and suppresses its kinase activity.The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13.SOCS1 regulates the JAK/STAT signal-transduction pathway.Moreover,it contributes to protection against hepatic injury and fibrosis,and may also protect against hepatocarcinogenesis. |
| Uniprot ID | O15524 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | suppressor of cytokine signaling 1 |
| 蛋白名全称 | Suppressor of cytokine signaling 1(SOCS-1) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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