产品货号：
Z26975
中文名称：
SPG15/ZFYVE26抗体
英文名称：
Anti-SPG15/ZFYVE26 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SPG15/ZFYVE26 Antibody |
| 指标别名 | SPG15;FYVE-CENT;KIAA0321;Zinc finger FYVE domain-containing protein 26;FYVE domain-containing centrosomal protein |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC |
| 基因名称 | ZFYVE26 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human ZFY26 protein. |
| 计算分子量 | 285KD |
| 成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
| 纯化方式 | ZFY26 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders.?Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration.SPG15 is the second gene known to be responsible for ARHSP-TCC in the Italian population.Mutations in this gene are associated with autosomal recessive spastic paraplegia-15.SPG15 encodes a protein containing a FYVE zinc finger binding domain which is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane.SPG15 mRNA is widely distributed in human tissues,as well as in rat embryos,suggesting a possible role for this protein during embryonic development.SPG15 co-localizes partially with endoplasmic reticulum and endosome markers,suggesting a role in intracellular trafficking. |
| Uniprot ID | Q68DK2 |
| 基因名全称 | Zinc finger FYVE domain-containing protein 26 |
| 蛋白名全称 | Zinc finger FYVE domain-containing protein 26 |
| 推荐稀释比 | IHC-p 1:50～300 |
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