产品货号：
Z26974
中文名称：
SPG15/ZFYVE26抗体
英文名称：
Anti-SPG15/ZFYVE26 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SPG15/ZFYVE26 Antibody |
| 指标别名 | SPG15,FYVE-CENT,KIAA0321,Zinc finger FYVE domain-containing protein 26,FYVE domain-containing centrosomal protein |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IF |
| 基因名称 | ZFYVE26 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SPG15 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human SPG15.The immunogen is located within amino acids 1710 - 1760 of SPG15. |
| 计算分子量 | 285kDa |
| 成分 | SPG15 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SPG15 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders.?Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration.SPG15 is the second gene known to be responsible for ARHSP-TCC in the Italian population.Mutations in this gene are associated with autosomal recessive spastic paraplegia-15.SPG15 encodes a protein containing a FYVE zinc finger binding domain which is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane.SPG15 mRNA is widely distributed in human tissues,as well as in rat embryos,suggesting a possible role for this protein during embryonic development.SPG15 co-localizes partially with endoplasmic reticulum and endosome markers,suggesting a role in intracellular trafficking. |
| Uniprot ID | Q68DK2 |
| 基因名全称 | Zinc finger,FYVE domain containing 26 |
| 蛋白名全称 | Zinc finger,FYVE domain containing 26 |
| 推荐稀释比 | SPG15 antibody can be used for detection of SPG15 by Western blot at 1 ～ 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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