产品货号:
Z26955
中文名称:
SOD2抗体
英文名称:
Anti-SOD2 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SOD2 Antibody |
指标别名 | IPO B;Mn SOD;MNSOD;SOD2;SODM |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | SOD2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human SOD-2. |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | SOD2(Superoxide Dismutase 2),also called IPO-B or MNSOD,is a mitochondrial matrix enzyme that scavenges oxygen radicals produced by the extensive oxidation-reduction and electron transport reactions occurring in mitochondria.This gene is a member of the iron/manganese superoxide dismutase family.Using a somatic cell hybrid panel containing different segments of chromosome 6,they demonstrated that SOD2 is located in the region 6q25.3-qter which,together with the FISH analysis,indicated that SOD2 is in the distal portion of 6q25.The SOD2 gene encodes an intramitochondrial free radical scavenging enzyme that is the first line of defense against superoxide produced as a byproduct of oxidative phosphorylation.Adeno-associated viral delivery of the human SOD2 gene resulted in suppression of optic nerve degeneration and rescue of retinal ganglion cells.The findings suggested that reactive oxygen species contributed to retinal cell death and optic nerve damage in mice with complex I deficiency,and that expression of SOD2 attenuated the disease process. |
Uniprot ID | P04179 |
推荐稀释比 | WB 1:1000~2000 IHC 1:200~500 |
相关搜索:SOD2抗体,SOD2多抗,Anti-SOD2 Antibody