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所在位置:所有产品 > 抗体抗原 > 一抗 > SNRPN抗体
SNRPN抗体图片
产品货号:
Z26919
中文名称:
SNRPN抗体
英文名称:
Anti-SNRPN Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-SNRPN Antibody
指标别名HCERN3;PWCR;RT LI;SM D;Sm N;Sm protein D;Sm protein N;SMN;SNRNP N;SNRPN;SNURF SNRPN
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,IHC,ICC
基因名称SNRPN
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the N-terminus of human SNRPN(31-48aa FKAFDKHMNLILCDCDEF),identical to the related rat and mouse sequences.
实际分子量25KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料SNRPN(Small Nuclear Ribonucleoprotein Polypeptide N),also called SMN,is a bicistronic imprinted gene that encodes 2 polypeptides,the SmN splicing factor,which is involved in RNA processing,and the SNRPN upstream reading frame(SNURF) polypeptide.The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family.SNRPN also encodes a long alternatively spliced transcript containing several small nucleolar RNAs(snoRNAs) and extends downstream to partially overlap the UBE3A gene in the antisense orientation.PWS arises from loss of function of genes in this region expressed exclusively from the paternal chromosome,suggesting that SNRPN may play a role in its etiology.The SNRPN gene is mapped on 15q11.2.Analysis of maternal DNA and of SNRPN cDNA confirmed that the maternal allele is not expressed in fetal brain and heart.Deletions in the transcription unit of the imprinted SNRPN gene occur in patients who have PWS or Angelman syndrome because of a parental imprint switch failure in this chromosomal domain.
Uniprot IDP63162
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称small nuclear ribonucleoprotein polypeptide N
蛋白名全称Small nuclear ribonucleoprotein-associated protein N(snRNP-N)
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunocytochemistry 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:SNRPN抗体SNRPN多抗Anti-SNRPN Antibody
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