产品货号：
Z26818
中文名称：
SIGLEC11抗体
英文名称：
Anti-SIGLEC11 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SIGLEC11 Antibody |
| 指标别名 | Sialic acid-binding Ig-like lectin 11,Sialic acid-binding lectin 11 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | SIGLEC11 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Siglec11 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human Siglec11.The immunogen is located within the last 50 amino acids of Siglec11. |
| 计算分子量 | 76kDa |
| 成分 | Siglec11 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Siglec11 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Siglecs are sialic acid-binding lectins of the immunoglobulin superfamily that are mainly expressed in cells of the hematopoietic system.Siglec11 is unlike other siglecs in that it binds specifically to alpha2-8-linked sialic acids and is not found in peripheral blood leukocytes but instead on macrophages of various tissues.Siglec11 is highly homologous to Siglec10 over their extracellular domain but not over their cytoplasmic domain,suggesting that Siglec11 arose through gene duplication followed by a recombination event involving another ancestral siglec gene.Following treatment of Siglec11-transfected cells with pervanadate,Siglec11 becomes tyrosine-phosphorylated and strongly associates with SHP-1 and SHP-2.At least five isoforms of Siglec11 are known to exist.Siglec11 antibody will not cross-react with Siglec10. |
| Uniprot ID | Q96RL6 |
| 基因名全称 | Sialic acid binding Ig-like lectin 11 |
| 蛋白名全称 | Sialic acid binding Ig-like lectin 11 |
| 推荐稀释比 | Siglec11 antibody can be used for detection of Siglec11 by Western blot at 1μg/mL.Despite its predicted size,Siglec11 migrates at a higher than expected molecular weight in SDS-PAGE.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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