产品货号：
Z26799
中文名称：
SINHCAF抗体
英文名称：
Anti-SINHCAF Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SINHCAF Antibody |
| 指标别名 | SINHCAF;C12orf14;FAM60A;L4;SIN3-HDAC complex-associated factor;Protein FAM60A;Tera protein homolog |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | SINHCAF |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human SINHCAF recombinant protein (Position:M1-W221). |
| 实际分子量 | 28～30KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | FAM60A,also known as Protein FAM60A,or Tera protein homolog,and encoded by the gene FAM60A/C12orf14,is a subunit of the Sin3 deacetylase complex (Sin3/HDAC) that is important for the repression of genes.The SIN3A-HDAC complex deacetylates histones thereby repressing gene transcription.FAM60A specifically impacts genes encoding components of the TGF-beta signaling pathway and promoters of important proteins like cyclin D1.FAM60A activity peaks during G1 and S phases of the cell cycle and is up regulated in many carcinoma and tumor tissues.Additionally,loss of FAM60A leads to a change in cell morphology,an increase in cell migration,increased histone acetylation at the cyclin D1 promoter and elevated levels of cyclin D1 mRNA and protein.Furthermore,depletion of FAM60A altered the periodic association of HDAC1 with the cyclin D1 promoter,increased cyclin D1 expression at all cell cycle phases,and caused premature S phase entry. |
| Uniprot ID | Q9NP50 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | SIN3-HDAC complex associated factor |
| 蛋白名全称 | SIN3-HDAC complex-associated factor |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：SINHCAF抗体，SINHCAF多抗，Anti-SINHCAF Antibody