产品货号：
Z26794
中文名称：
SIPA1L1抗体
英文名称：
Anti-SIPA1L1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SIPA1L1 Antibody |
| 指标别名 | E6 targeted protein 1,E6TP1,KIAA0440,SIPA1 like protein 1,SIPA1L1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | SIPA1L1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SIPA1L1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human SIPA1L1.The immunogen is located within amino acids 40 - 90 of SIPA1L1. |
| 计算分子量 | 200kDa |
| 成分 | SIPA1L1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SIPA1L1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Signal-induced proliferation associated-like protein 1 (SIPA1L1) is a member of the SIPA1 family of RapGAPs.SIPA1L1 was initially identified as a binding partner and degradation target of the E6 oncoprotein of high-risk papillomaviruses.Recently,it was discovered that Casein kinase I epsilon (CKIe),a Wnt-regulated kinase that regulates Wnt/b-catenin signaling,also can bind to the carboxy-terminus of SIPA1L1.CKIe phosphorylates SIPA1L1,thereby reducing its stability and alleviating its inhibition of Rap1,a protein required for Wnt8/CKIe-mediated gastrulation during embryogenesis,suggesting SIPA1L1 plays important roles in embryo development as well as control of cell proliferation. |
| Uniprot ID | O43166 |
| 基因名全称 | Signal-induced proliferation-associated 1 like 1 |
| 蛋白名全称 | Signal-induced proliferation-associated 1 like 1 |
| 推荐稀释比 | SIPA1L1 antibody can be used for detection of SIPA1L1 by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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