产品货号：
Z26787
中文名称：
SIP1/GEMIN2抗体
英文名称：
Anti-SIP1/GEMIN2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SIP1/GEMIN2 Antibody |
| 指标别名 | Component of gems 2;Gemin 2;GEMIN2;SIP1;SIP1 delta;SMN interacting protein 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | GEMIN2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SIP1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human SIP1.The immunogen is located within the last 50 amino acids of SIP1. |
| 计算分子量 | 32kDa |
| 成分 | SIP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SIP1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | SIP1 is one of the proteins found in the SMN complex,which consists of the survival of motor neuron (SMN) protein and several gemin proteins.The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing.SIP1 interacts directly with the SMN and it is required for formation of the SMN complex.A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.However,knockdown of the SIP1 mRNA in motor neurons showed normal motor axons while that of SMN mRNA did show abnormal motor axon outgrowth,indicating that SIP1 may have additional roles outside of the SMN complex. |
| Uniprot ID | O14893 |
| 基因名全称 | Gem nuclear organelle associated protein 2 |
| 蛋白名全称 | Gem nuclear organelle associated protein 2 |
| 推荐稀释比 | SIP1 antibody can be used for detection of SIP1 by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunocytochemistry starting at 4μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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