产品货号：
Z26744
中文名称：
SMURF2抗体
英文名称：
Anti-SMURF2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SMURF2 Antibody |
| 指标别名 | SMAD specific E3 ubiquitin protein ligase 2;SMURF2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | SMURF2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SMURF2 antibody was raised against a 17 amino acid peptide near the amino terminus of human SMURF2.The immunogen is located within amino acids 140 - 190 of SMURF2. |
| 计算分子量 | 86kDa |
| 成分 | SMURF2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SMURF2 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | SMURF2 (SMAD ubiquitin regulatory factor 2) is a negative regulator of TGF-beta signaling (1).SMURF1 and SMURF2 are members of HECT domain E3 ubiquitin ligase which are involved in the enzymatic reactions of the Ub conjugating pathway (1,2).SMURF2 is widely expressed and was initially identified as an inhibitor of TGF-beta/BMP signaling by targeting R-Smads and TGF type I receptor for ubiquitination and degradation (3).Studies have shown that SMURF2 functions as a tumor suppressor by maintaining genomic stability through targeting RNF20 (3).SMURF2 associates constitutively with SMAD7 (4). |
| Uniprot ID | Q9HAU4 |
| 基因名全称 | SMAD specific E3 ubiquitin protein ligase 2 |
| 蛋白名全称 | SMAD specific E3 ubiquitin protein ligase 2 |
| 推荐稀释比 | SMURF2 antibody can be used for detection of SMURF2 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for Immunohistochemistry at 2μg/mL.For Immunoflorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples.All other applications and species not yet tested. |
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