产品货号：
Z26657
中文名称：
SKA3抗体
英文名称：
Anti-SKA3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SKA3 Antibody |
| 指标别名 | RAMA1;C13orf3;RAMA1;Spindle and kinetochore-associated protein 3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | SKA3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SKA3 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human SKA3.The immunogen is located within amino acids 290 - 340 of SKA3. |
| 计算分子量 | 46kDa |
| 成分 | SKA3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SKA3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Upon entry into mitosis,the cell's microtubule (MT) network forms the mitotic spindle,allowing the segregation of paired chromosomes.Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs.A recently discovered spindle and kinetochore complex,comprised of proteins SKA1,SKA2,and SKA3,has been found to be required for stable KT-MT interactions and timely anaphase onset.Like with SKA1 or SKA2,depletion of SKA3 by siRNA delays anaphase transition,resulting in a prolonged a metaphase-like state.These SKA3-depleted cells accumulate high levels of the checkpoint protein Bub1 at kinetochores,suggesting the SKA complex plays a key role in spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis. |
| Uniprot ID | Q8IX90 |
| 基因名全称 | Spindle and kinetochore associated complex subunit 3 |
| 蛋白名全称 | Spindle and kinetochore associated complex subunit 3 |
| 推荐稀释比 | SKA3 antibody can be used for detection of SKA3 by Western blot at 0.5 ～ 1μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
相关搜索：SKA3抗体，SKA3多抗，Anti-SKA3 Antibody