产品货号:
Z26612
中文名称:
SLFN11抗体
英文名称:
Anti-SLFN11 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SLFN11 Antibody |
指标别名 | SLFN11' Schlafen family member 11 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,IHC,FCM,ELISA |
基因名称 | SLFN11 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human SLFN11 recombinant protein (Position:P114-D794). |
实际分子量 | 103KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Schlafen family member 11 is a protein that in humans is encoded by the SLFN11 gene.SLFN11 is a nuclear protein that belongs to the Schlafen (SLFN) family of genes involved in cell cycle regulation and growth inhibition.Expression of SLFN11 predicts sensitivity of cancer cell lines to DNA-damaging agents.Evidence suggests that in the presence of DNA-targeted therapies,SLFN11 is recruited to stressed replication forks where it blocks replication leading to cell death.SLFN11 is being explored as a predictive biomarker for response to DNA-targeted therapies. |
Uniprot ID | Q7Z7L1 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | schlafen family member 11 |
蛋白名全称 | Schlafen family member 11 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section IHC 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells ELISA 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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