产品货号：
Z26484
中文名称：
SHBG抗体
英文名称：
Anti-SHBG antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SHBG antibody |
| 指标别名 | ABP;Androgen binding protein;SBP;sex hormone binding globulin;Sex steroid binding protein;SHBG;TEBG |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | SHBG |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human SHBG recombinant protein (Position:P32-H402). |
| 实际分子量 | 44KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to the sex hormones,androgen and estrogen.SHBG is produced mostly by the liver and is released into the bloodstream.Other sites that produce SHBG include the brain,uterus,testes,and placenta.SHBG has both enhancing and inhibiting hormonal influences.It decreases with high levels of insulin,growth hormone,insulin-like growth factor 1 (IGF-1),androgens,prolactin and transcortin.High estrogen,andthyroxine cause it to increase.It has been found that the monosaccharides glucose and fructose reduced human SHBG production by hepatocytes,irrespective of the presence of insulin,by downregulation of hepatocyte nuclear factor-4A and replacement of HNF4A by COUP-TFI at a cis-element within the human SHBG promoter,coincident with repression of its transcriptional activity. |
| Uniprot ID | P04278 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | sex hormone-binding globulin |
| 蛋白名全称 | Sex hormone-binding globulin |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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