产品货号：
Z26394
中文名称：
SIVA/SIVA1抗体
英文名称：
Anti-SIVA/SIVA1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SIVA/SIVA1 Antibody |
| 指标别名 | SIVA1;SIVA;Apoptosis regulatory protein Siva;CD27-binding protein;CD27BP |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IF |
| 基因名称 | SIVA1 |
| 抗体来源 | Chicken |
| 抗体类型 | IgY |
| 免疫原 | SIVA antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human SIVA.The immunogen is located within the first 50 amino acids of SIVA. |
| 计算分子量 | 19kDa |
| 成分 | SIVA Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SIVA Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | SIVA plays an important role in the apoptotic pathway induced by the CD27 antigen,a member of the tumor necrosis factor receptor (TFNR) superfamily.SIVA is a small cysteine-rich protein with a unique N-terminal amphipathic helical region,a death domain homology region (DDHR) and a C-terminal cysteine-rich B-box-like or zinc-finger-like structure.The DDHR domain binds to CD27 and induces apoptosis in T cells through a caspase-dependent mitochondrial pathway.SIVA inhibits BCL2L1 isoform Bcl-xL anti-apoptotic activity and inhibits activation of NF百-B and promotes T-cell receptor-mediated apoptosis.SIVA represents a potential therapeutic target for the treatment of neuronal cell death diseases. |
| Uniprot ID | O15304 |
| 基因名全称 | SIVA1,apoptosis-inducing factor |
| 蛋白名全称 | SIVA1,apoptosis-inducing factor |
| 推荐稀释比 | SIVA antibody can be used for detection of EPAC1 by Western blot at 1μg/mL.Antibody can also be used for immunofluorescence starting at 20μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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