产品货号:
Z26385
中文名称:
SIRT3抗体
英文名称:
Anti-SIRT3 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SIRT3 Antibody |
指标别名 | hSIRT3;SIR2 like protein 3;SIR2L3;SIRT3 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB |
基因名称 | SIRT3 |
抗体来源 | Chicken |
抗体类型 | IgY |
免疫原 | SIRT3 antibody was raised against a 17 amino acid synthetic peptide near the center of human SIRT3.The immunogen is located within amino acids 180 - 230 of SIRT3. |
计算分子量 | 44kDa |
成分 | SIRT3 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | SIRT3 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism,growth and differentiation,inflammation,cellular survival,as well as in senescence,lifespan extension and several age-related diseases.Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) and SIRT3 is the only sirtuin whose increased expression has been shown to correlate with an extended life span in humans.It is localized in the mitochondrial matrix,where it regulates the acetylation levels of metabolic enzymes,including acetyl coenzyme A synthetase 2.SIRT3 is stress-responsive and its increased expression protects myocytes from genotoxic and oxidative stress-mediated cell death. |
Uniprot ID | Q9NTG7 |
基因名全称 | Sirtuin 3 |
蛋白名全称 | Sirtuin 3 |
推荐稀释比 | SIRT3 antibody can be used for detection of SIRT3 by Western blot at 1 ~ 2μg/mL.Antibody validated:Western Blot in mouse samples.All other applications and species not yet tested. |
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