产品货号：
Z26373
中文名称：
SF3B3抗体
英文名称：
Anti-SF3B3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SF3B3 Antibody |
| 指标别名 | KIAA0017;RSE1;SAP 130;SAP130;SF3b130;SF3B3;Splicing factor 3B subunit 3;STAF130 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IF,ICC/IF,FCM,ELISA |
| 基因名称 | SF3B3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human SF3B3 recombinant protein (Position:R728-Q1181). |
| 实际分子量 | 136KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Splicing factor 3B subunit 3 is a protein that in humans is encoded by the SF3B3 gene.This gene encodes subunit 3 of the splicing factor 3b protein complex.Splicing factor 3b,together with splicing factor 3a and a 12S RNA unit,forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP).The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA.Splicing factor 3b is also a component of the minor U12-type spliceosome.Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex,and the TFTC (TATA-binding-protein-free TAF(II)-containing complex).These complexes may function in chromatin modification,transcription,splicing,and DNA repair. |
| Uniprot ID | Q15393 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | splicing factor 3b subunit 3 |
| 蛋白名全称 | Splicing factor 3B subunit 3 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunofluorescence (IF) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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