产品货号：
Z26341
中文名称：
Serotonin transporter/SLC6A4抗体
英文名称：
Anti-Serotonin transporter/SLC6A4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Serotonin transporter/SLC6A4 Antibody |
| 指标别名 | 5 HTT;5 HTTLPR;5HT transporter;5HTT;hSERT;HTT;OCD1;serotonin transporter;SERT;SLC6A4 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | SLC6A4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human SLC6A4 (57-85aa DDTRHSIPATTTTLVAELHQGERETWGKK),different from the related mouse and rat sequences by six amino acids. |
| 实际分子量 | 70～90KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SLC6A4 (Solute carrier family 6,member 4),also known as SERT (serotonin transporter),is a monoamine transporter protein.The SLC6A4 gene spans 31kb and contains 14 exons.This protein integral membrane protein transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons.This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner.This protein is the target of many antidepressant medications,including those of the SSRI class.It is a member of the sodium:neurotransmitter symporter family.A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome,aggressive behavior in Alzheimer disease patients,post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma. |
| Uniprot ID | P31645 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | solute carrier family 6 (neurotransmitter transporter,serotonin),member 4 |
| 蛋白名全称 | Sodium-dependent serotonin transporter |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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