产品货号：
Z26283
中文名称：
SKP1抗体
英文名称：
Anti-SKP1 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SKP1 Antibody |
| 指标别名 | EMC19;NET19;OCP 2;OCP II;OCP2;Organ of Corti protein 2;Organ of Corti protein II;p19A;p19skp1;SIII;SKP1;SKP1A;TCEB1L |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IP |
| 基因名称 | SKP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 152-163 of Human SKP1 (C-terminus) coupled to KLH. |
| 成分 | 0.01% (w/v) Sodium Azide |
| 纯化方式 | This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.This product reacts with human SKP1.Cross-reactivity is expected against mouse SKP1 based on a high degree of sequence homology.Cross-reactivity with other SKP1 proteins or SKP1 from other sources is not known. |
| 浓度 | 85mg/mL by Refractometry |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | SKP1 is also known as S-phase kinase-associated protein 1A,Cyclin A/CDK2-associated protein p19,p19A,p19skp1,RNA polymerase II elongation factor-like protein,Organ of Corti protein 2,OCP-II protein,OCP-2,Transcription elongation factor B,and SIII.SKP1 is an essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex,which mediates the ubiquitination of proteins involved in cell cycle progression,signal transduction and transcription.In the SCF complex,SKP1 serves as an adapter that links the F-box protein to CUL1.SKP1 interacts directly with CUL1 and F-box proteins,such as BTRC and SKP2,in the SCF complex.SKP1 also interacts with FBX29 and the cyclin A/CDK2 complex.SKP1 is part of a SCF-like complex consisting of CUL7,RBX1,SKP1 and FBXW8 and is also a component of a E3 ubiquitin ligase complex containing UBE2D1,SIAH1,CACYBP/SIP,SKP1A,APC and TBL1X. |
| Uniprot ID | P63208 |
| 推荐稀释比 | ELISA:1:2,000 - 1:10,000 IHC:User Optimized WB:1:500 - 1:1,000 |
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