产品货号：
Z26052
中文名称：
SARS-CoV-2 NSP1/Leader protein抗体
英文名称：
Anti-SARS-CoV-2 NSP1/Leader protein Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SARS-CoV-2 NSP1/Leader protein Antibody |
| 指标别名 | Replicase polyprotein 1ab;pp1ab;ORF1ab polyprotein;nsp10;Non-structural protein 10;Growth factor-like peptide;GFL;rep |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA |
| 基因名称 | rep |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGVLPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped,positive-sense,single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19).Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells.Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles,nonstructural proteins that direct virus assembly,transcription,replication and host control and accessory proteins whose function has not been determined.~ORF1ab,the largest gene,contains overlapping open reading frames that encode polyproteins PP1ab and PP1a.The polyproteins are cleaved to yield 16 nonstructural proteins,NSP1-16.Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event.The proteins,based on similarity to other coronaviruses,include the papain-like proteinase protein (NSP3),3C-like proteinase (NSP5),RNA-dependent RNA polymerase (NSP12,RdRp),helicase (NSP13,HEL),endoRNAse (NSP15),2'-O-Ribose-Methyltransferase (NSP16) and other nonstructural proteins.SARS-CoV-2 nonstructural proteins are responsible for viral transcription,replication,proteolytic processing,suppression of host immune responses and suppression of host gene expression.The RNA-dependent RNA polymerase is a target of antiviral therapies. |
| Uniprot ID | P0DTC1/P0DTD1 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | ORF1a polyprotein;ORF1ab polyprotein |
| 蛋白名全称 | Host translation inhibitor nsp1 |
| 推荐稀释比 | ELISA 1:100～1000 |
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