产品货号：
Z26025
中文名称：
SATB2抗体
英文名称：
Anti-SATB2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SATB2 Antibody |
| 指标别名 | DNA binding protein SATB2;KIAA1034;SATB homeobox 2;SATB2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | SATB2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SATB2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of the human SATB2.The immunogen is located within the first 50 amino acids of SATB2. |
| 计算分子量 | 83kDa |
| 成分 | SATB2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SATB2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Human special AT-rich sequence-binding protein-2 (SATB2) is a nuclear matrix/scaffold-associated region DNA-binding protein.Like its homolog SATB1,SATB2 selectively binds double-stranded,special AT-rich DNA sequences,but is expressed primarily in a subset of postmitotic,differentiating neurons in the neocortex.Mice deficient in SATB exhibit craniofacial abnormalities and defects in osteoblast differentiation and function.SATB2 also interacts with and enhances the activity of Runx2 and ATF4,two transcription factors that regulate osteoblast differentiation,indicating that SATB2 acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.Recent experiments have shown that SATB2 interacts with histone deacetylase 1 and metastasis-associated protein 2,two proteins that are involved in chromatin remodeling,suggesting that SATB2 may also be involved in mediating epigenetic influences during cortical development. |
| Uniprot ID | Q9UPW6 |
| 基因名全称 | SATB homeobox 2 |
| 蛋白名全称 | SATB homeobox 2 |
| 推荐稀释比 | SATB2 antibody can be used for detection of SATB2 by Western blot at 2 ～ 4μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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