产品货号：
Z25904
中文名称：
SCF/KITLG抗体
英文名称：
Anti-SCF/KITLG Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SCF/KITLG Antibody |
| 指标别名 | c Kit ligand;KIT ligand;Kitl;KITLG;KL 1;Mast cell growth factor;MGF;SCF;SF;SHEP7;Stem cell factor |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | KITLG |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-SCF antibody was raised against a peptide corresponding to 18 amino acids near the center of human SCF.The immunogen is located within amino acids 100-150 of SCF. |
| 计算分子量 | 31kDa |
| 成分 | SCF Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SCF Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways.Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3,PLC-gamma,Jak/STAT,and MAP kinase pathways.SCF expression leads to the induction of mast cell survival and the expression and release of histamine,pro-inflammatory cytokines and chemokines.The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels,mast cell and eosinophil infiltration,IL-4 production and airway hyperresponsiveness,suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma.At least two isoforms of SCF are known to exist. |
| Uniprot ID | P21583 |
| 基因名全称 | KIT ligand |
| 蛋白名全称 | KIT ligand |
| 推荐稀释比 | WB:1～2μg/mL;IHC:2.5μg/mL;IF:20μg/mL.Antibody validated:Western Blot in human,mouse and rat samples;Immunohistochemistry in mouse samples;Immunofluorescence in human samples.All other applications and species not yet tested. |
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