产品货号：
Z25860
中文名称：
SDHB抗体
英文名称：
Anti-SDHB Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SDHB Antibody |
| 指标别名 | IP;PGL4;SDH;SDH1;SDHB;SDHIP |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | SDHB |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human SDHB(42-59 FAIYRWDPDKAGDKPHMQ),different from the related rat sequence by one amino acid and mouse sequence by two amino acids. |
| 实际分子量 | 29KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SDHB(Succinate Dehydrogenase Complex,Subunit B,iron sulfur protein),also known as iron-sulfur subunit of complex II(Ip) or SDH2,HOMOLOG OF,is a protein that in humans is encoded by the SDHB gene.SDHB is one of four protein subunits forming succinate dehydrogenase,the other three being SDHA,SDHC and SDHD.The SDHB subunit is connected to the SDHA subunit on the hydrophilic,catalytic end of the SDH complex.The SDHB gene is mapped on 1p36.13.The entire SDHB transcript is encoded by 8 exons within approximately 40kb by Au et al(1995).Pollard et al.(2005) stated that the nuclear-encoded Krebs cycle enzymes fumarate hydratase and succinate dehydrogenases like SDHB act as tumor suppressors,and germline mutations in these genes predispose individuals to leiomyomas and renal cancer and to paragangliomas,respectively.In affected members of families with paragangliomas-4,mutations were identified in the SDHB gene. |
| Uniprot ID | P21912 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | succinate dehydrogenase complex,subunit B,iron sulfur(Ip) |
| 蛋白名全称 | Succinate dehydrogenase[ubiquinone] iron-sulfur subunit,mitochondrial |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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