产品货号：
Z25840
中文名称：
RUNX1抗体
英文名称：
Anti-RUNX1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RUNX1 Antibody |
| 指标别名 | AML1;AML1 EVI 1;AMLCR1;CBF alpha 2;CBFA2;EVI 1;Oncogene AML 1;PEA2 alpha B;PEBP2 alpha B;PEBP2aB;RUNX1;RUNX1 (middle) |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IHC-F |
| 基因名称 | RUNX1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human RUNX1(200-233aa ELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFN),identical to the related mouse and rat sequences. |
| 实际分子量 | 49KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Runt-related transcription factor 1 (RUNX1),also known as AML1 or CBFA2,is a protein that in humans is encoded by the RUNX1 gene.It belongs to the Runt-related transcription factor (RUNX) family of genes which are also called core binding factor-α (CBFα).RUNX1 is mapped to 21q22.12.RUNX1 is a transcription factor that regulates the differentiation of hematopoietic stem cells into mature blood cells.RUNX proteins form a heterodimeric complex with CBFβ which confers increased DNA binding and stability to the complex.Chromosomal translocations involving the RUNX1 gene are associated with several types of leukemia including M2 AML.Mutations in RUNX1 are implicated in cases of breast cancer. |
| Uniprot ID | Q01196 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | runt-related transcription factor 1 |
| 蛋白名全称 | Runt-related transcription factor 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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