产品货号：
Z25835
中文名称：
RUSC1抗体
英文名称：
Anti-RUSC1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RUSC1 Antibody |
| 指标别名 | NESCA;NESCA;RUN and SH3 domain-containing protein 1;New molecule containing SH3 at the carboxy-terminus;Nesca |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | RUSC1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | RUSC1 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human RUSC1.The immunogen is located within amino acids 780 - 830 of RUSC1. |
| 计算分子量 | 96kDa |
| 成分 | RUSC1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | RUSC1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | RUSC1,also known as NESCA,shares with the related protein RUSC2 a common domain structure of RUN,leucine zipper and SH3 domain in addition to over 30% amino acid identity.RUSC1 is an adapter protein that can bind to the TrkA receptor and is necessary in the NGF-induced neurite growth of PC12 cells.RUSC1 has also been shown to interact with I百B kinase- (IKK-) gamma,the regulatory subunit of the IKK complex that is required for NF-百B activation in many signaling pathways such as TNF-R or the TLR pathways.RUSC1 can also bind to the E3 ubiquitin ligase TRAF6,which then catalyzes RUSC1 polyubiquitination.Since overexpression of RUSC1 strongly inhibits TRAF6-mediated polyubiquitination of IKK-gamma,RUSC1 may be a link in the IKK-gamma-mediated NF-百B activation pathway. |
| Uniprot ID | Q9BVN2 |
| 基因名全称 | RUN and SH3 domain containing 1 |
| 蛋白名全称 | RUN and SH3 domain containing 1 |
| 推荐稀释比 | RUSC1 antibody can be used for detection of RUSC1 by Western blot at 1μg/mL.Antibody validated:Western Blot in mouse samples.All other applications and species not yet tested. |
相关搜索：RUSC1抗体，RUSC1多抗，Anti-RUSC1 Antibody