产品货号：
Z25834
中文名称：
RWDD3抗体
英文名称：
Anti-RWDD3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RWDD3 Antibody |
| 指标别名 | RSUME;RSUME;RWD domain-containing protein 3;RWD-containing sumoylation enhancer |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | RWDD3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | RWDD3 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RWDD3.The immunogen is located within the last 50 amino acids of RWDD3. |
| 计算分子量 | 31kDa |
| 成分 | RWDD3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | RWDD3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | RWDD3 (RSUME),a small RWD-containing protein,has a central role in sumoylation by enhancing SUMO conjugation in the regulatory network of immune-inflammatory signals.RWDD3 increases I百Beta sumoylation and stability.In addition,RWDD3 inhibits TNF-汐-induced kappaB-LUC (Luciferase) reporter activity,showing the functional consequence of I百Beta increased stability.RSUME-enhanced sumoylation of I百Beta leads to the inhibition of NF-百Beta activity on two well-known inflammatory genes,IL-8 and cyclooxygenase-2 (Cox-2) and therefore may also favor anti-inflammatory pathways.Expression of RWDD3 was induced under hypoxic conditions and it has a potential role during vascularization.Both BMP-4 and RWDD3 may be interesting targets for inhibiting steps involved in pituitary tumorigenesis. |
| Uniprot ID | Q9Y3V2 |
| 基因名全称 | RWD domain containing 3 |
| 蛋白名全称 | RWD domain containing 3 |
| 推荐稀释比 | RWDD3 antibody can be used for detection of RWDD3 by Western blot at 1μg/mL.Antibody validated:Western Blot in rat samples.All other applications and species not yet tested. |
相关搜索：RWDD3抗体，RWDD3多抗，Anti-RWDD3 Antibody