产品货号:
Z25780
中文名称:
RCAN2抗体
英文名称:
Anti-RCAN2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-RCAN2 Antibody |
指标别名 | Calcipressin 2;CSP2;DSCR1L1;hRCN2;MCIP2;RCAN2;regulator of calcineurin 2;ZAKI 4;ZAKI4 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | RCAN2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | RCAN2 antibody was raised against a 14 amino acid synthetic peptide near the center of human RCAN2.The immunogen is located within amino acids 70 - 120 of RCAN2. |
计算分子量 | 22kDa |
成分 | RCAN2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | RCAN2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Regulator of calcineurin 2 (RCAN2),also known as ZAKI4 and DSCR1L1,is expressed as two isoforms differing at their N-terminus.The longer of the two (isoform 1) is expressed exclusively in the brain,while isoform 2 is ubiquitously expressed,with highest expression in brain,heart,and muscle.Both isoforms bind to the catalytic subunit of calcineurin,a Ca++-dependent protein phosphatase involved in several neuronal functions,though their C-terminal region and inhibit calcineurin's activity.Unlike isoform 1 of RCAN2,the expression of the second isoform is not induced by the thyroid hormone T3.RCAN2 is a member of a family of three endogenous calcineurin regulators that are located near the minimal supernumerary fragment of chromosome 21 in individuals with Down syndrome,suggesting that they play a role in this syndrome.Multiple isoforms of RCAN2 are known to exist. |
Uniprot ID | Q9JHG2 |
基因名全称 | Regulator of calcineurin 2 |
蛋白名全称 | Regulator of calcineurin 2 |
推荐稀释比 | RCAN2 antibody can be used for detection of RCAN2 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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