产品货号：
Z25501
中文名称：
ROCK2抗体
英文名称：
Anti-ROCK2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ROCK2 Antibody |
| 指标别名 | KIAA0619;p164 ROCK 2;Rho kinase 2;ROCK2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | ROCK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ROCK2 recombinant protein (Position:E652-D923).Human ROCK2 shares 94.9% and 95.2% amino acid (aa) sequence identity with mouse and rat ROCK2,respectively. |
| 实际分子量 | 161KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Rho-associated kinase (ROCK),including the ROCK-I and ROCK-II isoforms,is a protein kinase involved in signaling from Rho to actin cytoskeleton.Serine/threonine kinase ROCK II/Rho kinase,which is an isozyme of ROCK I,is one of the targets for the small GTPase Rho.ROCK II regulates the formation of actin stress fibers and focal adhesions,cytokinesis,smooth muscle contraction,and the activation of c-fos serum response element.Sequencing analysis has shown that human ROCK II contains 1388 amino acid residues with a calculated molecular mass of approximately 161kDa.Fluorescence in situ hybridization analysis showed that the human ROCK II gene is located on chromosome 2p24.Thumkeo et al.concluded that ROCK-II is essential in inhibiting blood coagulation and maintaining blood flow in the endothelium-free labyrinth layer and that loss of ROCK-II leads to thrombus formation,placental dysfunction,intrauterine growth retardation,and fetal death. |
| Uniprot ID | O75116 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | Rho-associated,coiled-coil containing protein kinase 2 |
| 蛋白名全称 | Rho-associated protein kinase 2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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