产品货号:
Z25492
中文名称:
Roquin-1/RC3H1抗体
英文名称:
Anti-Roquin-1/RC3H1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Roquin-1/RC3H1 Antibody |
指标别名 | RNF198,ROQUIN,KIAA2025,RNF198,Roquin-1,RING finger and C3H zinc finger protein 1,Roquin |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | RC3H1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Rabbit polyclonal RC3H1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RC3H1.The immunogen is located within amino acids 1040 - 1090 of RC3H1. |
计算分子量 | 126kDa |
成分 | RC3H1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | RC3H1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The ring finger protein RC3H1,also known as Roquin,is a highly conserved member of the RING type ubiquitin ligase protein family whose M199R mutation leads to the excessive production of follicular helper T cells and germinal centers in the sanroque strain of mice,a strain with excessive IL-21 production and high titers of autoantibodies.The complete loss of RC3H1 induces early death and immune deregulation but not autoimmunity in RC3H1-null mice,suggesting that the mutant RC3H1 is more disruptive to the immune system than its complete loss. |
Uniprot ID | Q5TC82 |
基因名全称 | Ring finger and CCCH-type domains 1 |
蛋白名全称 | Ring finger and CCCH-type domains 1 |
推荐稀释比 | RC3H1 antibody can be used for detection of RC3H1 by Western blot at 1 ~ 2μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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