产品货号:
Z25447
中文名称:
RNF20抗体
英文名称:
Anti-RNF20 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-RNF20 Antibody |
指标别名 | BRE1;BRE1 A;BRE1A;hBRE1;KIAA2779;ring finger protein 20;RNF20 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | RNF20 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | RNF20 antibody was raised against a 19 amino acid peptide near the amino terminus of human RNF20.The immunogen is located within amino acids 130 - 180 of RNF20. |
计算分子量 | 114kDa |
成分 | RNF20 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | RNF20 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | RNF20 is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B.RNF20 selectively suppresses the expression of some genes such as several protooncogenes and growth-related genes,including many genes that are induced by epidermal growth factor by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS).In contrast,RNF20 also positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes.Together with the deubiquitinase USP44,RNF20 regulates stem cell differentiation by modulating H2B monoubiquitination. |
Uniprot ID | Q5VTR2 |
基因名全称 | Ring finger protein 20,E3 ubiquitin protein ligase |
蛋白名全称 | Ring finger protein 20,E3 ubiquitin protein ligase |
推荐稀释比 | RNF20 antibody can be used for detection of RNF20 by Western blot at 1 ~ 2μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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