产品货号：
Z25407
中文名称：
RPS6抗体
英文名称：
Anti-RPS6 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RPS6 Antibody |
| 指标别名 | 40S ribosomal protein S6;Cell and organelle markers;Phosphoprotein NP33;ribosomal protein S6;Ribosome Marker;RPS6 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | RPS6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human RPS6 (13-52aa QKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRI),identical to the related mouse and rat sequences. |
| 实际分子量 | 29KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Ribosomal protein S6 (rpS6) is a component of the 40S ribosomal subunit and is therefore thought to be involved in regulating translation.Ribosomes,the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit.Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit.The protein belongs to the S6E family of ribosomal proteins.It is the major substrate of protein kinases in the ribosome,with subsets of five C-terminal serine residues phosphorylated by different protein kinases.Phosphorylation is induced by a wide range of stimuli,including growth factors,tumor-promoting agents,and mitogens.Dephosphorylation occurs at growth arrest.The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA.As is typical for genes encoding ribosomal proteins,there are multiple processed pseudogenes of this gene dispersed through the genome.While the true function of rpS6 is currently under investigation,studies have shown that it is involved in the regulation of cell size,cell proliferation,and glucose homeostasis. |
| Uniprot ID | P62753 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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