产品货号：
Z25352
中文名称：
RGMB抗体
英文名称：
Anti-RGMB Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RGMB Antibody |
| 指标别名 | repulsive guidance molecule BMP co-receptor b;DRAGON;RGMB |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | RGMB |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human DRAGON/RGMB recombinant protein (Position:D47-R404). |
| 实际分子量 | 48KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Repulsive guidance molecule B (RGMb),also known as DRAGON (DRG11-responsive axonal guidance and outgrowth of neurite),is a bone morphogenetic protein (BMP) co-receptor of the repulsive guidance molecule family.In humans this protein is encoded by the RGMB gene.RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see also RGMA and RGMC) and contributes to the patterning of the developing nervous system.There is a potential association between RGMs and cancer bone metastasis,as RGMs coordinate bone morphogenetic protein (BMP) signaling.RGMB may act as a negative regulator in vitro in breast cancer and prostate cancer through BMP signalling.Furthermore,aberrant expression of RGMs was indicated in breast cancer.The perturbed expression was associated with disease progression and poor prognosis. |
| Uniprot ID | Q6NW40 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | repulsive guidance molecule BMP co-receptor b |
| 蛋白名全称 | RGM domain family member B |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
相关搜索：RGMB抗体，RGMB多抗，Anti-RGMB Antibody