产品货号:
Z25204
中文名称:
RIPK2抗体
英文名称:
Anti-RIPK2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-RIPK2 Antibody |
| 指标别名 | CARD3;CARDIAK;CCK;GIG30;Receptor interacting protein 2;RICK;RIP 2;RIP2;RIPK2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | RIPK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human RIP2/RIPK2 recombinant protein (Position:Y15-M540). |
| 实际分子量 | 61KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | RIPK2(Receptor-interacting serine/threonine-protein kinase 2),also known as CARD3,CARDIAK,RICK,RIP2,is an?enzyme?that in humans is encoded by the?RIPK2?gene.?It has 540-amino acid protein in length.?Northern blot analysis revealed that RICK is expressed in various human tissues as 2.5- and 1.8-kb mRNAs that differ due to alternative polyadenylation.RICK is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway.This gene encodes a member of the receptor-interacting protein(RIP) family of serine/threonine protein kinases.The encoded protein contains a C-terminal?caspase recruitment domain(CARD),and is a component of signaling complexes in both the innate and adaptive immune pathways.It is a potent activator of?NF-kappa B?and inducer of apoptosis in response to various stimuli,CARDIAK(CARD-containing ICE-associated kinase) specifically interacted with the CARD of ICE/caspase-1,and this interaction correlated with the processing of pro-caspase-1 and the formation of the active caspase-1 p20 subunit. |
| Uniprot ID | O43353 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | receptor interacting serine/threonine kinase 2 |
| 蛋白名全称 | Receptor-interacting serine/threonine-protein kinase 2 |
| 推荐稀释比 | Western blot(WB) 1:500~2000 Flow cytometry (FCM) 1~3μg/1×106 cells ELISA: 1:100~1000 |
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