产品货号：
Z25202
中文名称：
RIPK2抗体
英文名称：
Anti-RIPK2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RIPK2 Antibody |
| 指标别名 | CARD3;CARDIAK;CCK;GIG30;Receptor interacting protein 2;RICK;RIP 2;RIP2;RIPK2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | RIPK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | RICK antibody was raised against a peptide corresponding to 20 amino acids near the amino terminus of human RICK.The immunogen is located within the first 50 amino acids of RICK. |
| 计算分子量 | 61kDa |
| 成分 | RICK Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | RICK Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | RICK antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | Apoptosis is mediated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases.DD-containing serine/threonine kinase RIP regulates Fas-induced apoptosis.A novel CARD-containing serine/threonine kinase was recently identified and designated RICK/RIP2/CARDIAK for RIP-like interacting CLARP kinase,receptor interacting protein-2,and CARD-containing ICE associated kinase,respectively.RICK contains an N-terminal kinase catalytic domain and a C-terminal CARD domain.Overexpression of RICK induced apoptosis and activation of NF-百B and JNK.RICK interacts with members of the TRAF family,CLARP and caspase-1.Thus,RICK represents a novel kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1汕.The messenger RNA of RICK is expressed in multiple human tissues. |
| Uniprot ID | O43353 |
| 基因名全称 | Receptor-interacting serine-threonine kinase 2 |
| 蛋白名全称 | Receptor-interacting serine-threonine kinase 2 |
| 推荐稀释比 | RICK antibody can be used for detection of RICK by Western blot at 1μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human and mouse samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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