产品货号：
Z25181
中文名称：
PTPRF抗体
英文名称：
Anti-PTPRF Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PTPRF Antibody |
| 指标别名 | protein tyrosine phosphatase receptor type F;BNAH2;LAR;PTPRF |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | PTPRF |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human LAR (1167-1203aa EQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDK),different from the related mouse and rat sequences by four amino acids. |
| 实际分子量 | 240KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Receptor-type tyrosine-protein phosphatase F is an enzyme that in humans is encoded by the PTPRF gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth,differentiation,mitotic cycle,and oncogenic transformation.This PTP possesses an extracellular region,a single transmembrane region,and two tandem intracytoplasmic catalytic domains,and thus represents a receptor-type PTP.The extracellular region contains three Ig-like domains,and nine non-Ig like domains similar to that of neural-cell adhesion molecule.This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions,as well as in the control of beta-catenin signaling.An increased expression level of this protein was found in the insulin-responsive tissue of obese,insulin-resistant individuals,and may contribute to the pathogenesis of insulin resistance.Two alternatively spliced transcript variants of this gene,which encode distinct proteins,have been reported. |
| Uniprot ID | P10586 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | protein tyrosine phosphatase,receptor type,F |
| 蛋白名全称 | Receptor-type tyrosine-protein phosphatase F |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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